HD, its going to be an E85 only motor, no switching back to pump gas. Ive seen guys say there running 9:1 and 22+lbs boost on the stuff, As well as a turbo deal thats 8.5:1 with over 30lbs so It should be fine with the cylinder pressures. I dont think the blower in question will make those kind of crazy boost numbers. Thats the reason for the high comp/lower boost idea.
GT, I was thinking the same thing, small chamber and flat tops (or close to it). And if it was a Ford that would be no problem, lots of small chamber heads for those (down into the mid 70cc range). But I cant find any good aftermarkets like that for a Chevy. Theres got to be a way around the big dome piston deal. Those things are lumpy, bumpy and heavy.